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Important Changes to the iPLEDGE® REMS Take Effect November 15, 2026
The iPLEDGE REMS Sponsors have announced changes to the iPLEDGE REMS that take effect on November 15, 2026. The changes affect pregnancy testing, patient categories, the 19-day lockout, counseling documentation, and REMS educational materials. SDPA members who prescribe isotretinoin should review the updates below and adjust their practice workflows before the effective date.
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